Optimization of Rat Liver Microsomal Stability Assay Using HPLC
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چکیده
منابع مشابه
Monitoring by HPLC of Chamomile Flavonoids Exposed to Rat Liver Microsomal Metabolism
Three major flavonoid chamomile components (quercetin, apigenin-7-O-glucoside and rutin) were subjected to oxidative metabolism by cytochrome P-450 of rat liver microsomal preparations. Changes over time in their respective concentrations were followed using reversed-phase HPLC with UV detection. No clean-up had to be applied as only the specific flavonoid had to be separated from the backgroun...
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ژورنال
عنوان ژورنال: Journal of Biological Sciences
سال: 2008
ISSN: 1727-3048
DOI: 10.3923/jbs.2008.1110.1114